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产品目录

重组人SPINK4(丝氨酸蛋白酶抑制剂Kazal 4型)图片
产品货号:
JN1718
中文名称:
重组人SPINK4(丝氨酸蛋白酶抑制剂Kazal 4型)
英文名称:
Recombinant Human Serine Protease Inhibitor Kazal-Type 4
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gly27-Cys86在C端含有His标签。

SPINK4质量控制:>95%(还原性SDS-PAGE)

SPINK4制剂:液体

SPINK4保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。

关于SPINK4
Serine Protease Inhibitor Kazal-Type 4 (SPINK4) is a secreted protein containing one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine protease inhibitors of the Kazal type (SPINK) are functional and positional candidate genes for celiac disease (CD). SPINK1 plays an important role in protecting the pancreas against excessive trypsinogen activation. It is a potent natural inhibitor of pancreatic trypsin activity. SPINK1 mutations are associated with the development of acute and chronic pancreatitis and have been detected in all forms of chronic pancreatitis. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein contains a typical Kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK9 was identified in human skin. Its expression was strong in palmar epidermis, but not detectable or very low in non palmoplantar skin.
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